Lei Qian

Endothelial Bmal1 coordinates intrinsic and paracrine mechanisms to limit post-injury vascular restenosis

Circadian rhythms have been implicated in the regulation of cardiovascular physiology and disease. Disruption of circadian signaling has been linked to exaggerated neointimal hyperplasia and delayed endothelial repair. Bmal1, a core component of the molecular clock, plays a criti...