Lei Gong

Green Light‐Driven, Diastereoselective Synthesis of Pentasubstituted α ‐Trifluoromethylated Pyrrolidines via a Singlet Carbene Process

Comprehensive Summary Trifluoromethylated heterocycles represent privileged structural motifs in pharmaceuticals and agrochemicals, as the incorporation of a CF 3 group significantly enhances metabolic stability, lipophilicity, and bioactivity. Among these, α ‐trifluoromethyl pyr...