Lei Cai

Network-guided synthesis of antagonistic microbiota for suppressing maize stalk rot disease.

Plant-associated microbiomes play a crucial role in sustaining host health and fitness, but how pathogen invasion reshapes microbial interaction networks and how to leverage this for developing effective biocontrol strategies remain poorly understood. This study investigated the...

Delivery of miR-181a/b-1 enhances endochondral fracture repair by targeting PDK4 and regulating mitochondrial metabolism

We previously reported an in vitro pro-osteogenic function for miR-181a/b-1, in part, via increasing mitochondrial metabolism. The goal of this study was to determine the effect of miR-181a/b-1 on bone repair in vivo, and to discover metabolism-related mechanisms. Here we show th...