Leah Varner

Distinctive properties of the prion protein in the brain and retina in the amyloidosis associated with the PRNP F198S mutation

Abstract Prion protein (PrP) deposits in the form of diffuse and cored plaques occur in most gray matter areas of the brain of individuals affected by Gerstmann-Sträussler-Scheinker disease (GSS) associated with the F198S mutation in PRNP; however, the PrP deposits in the retina...