Laurentino Mendes Leal

Orbital Apex Involvement in Sinonasal Intestinal-Type Adenocarcinoma: Impact on Distant Metastasis and Mortality

Abstract Sinonasal intestinal-type adenocarcinoma (ITAC) is often diagnosed at advanced stages. Prognosis is strongly influenced by tumor extension into critical anatomical regions contiguous with the orbit and skull base, where achieving negative margins is challenging. To ident...