Lauren M. Bradford

A human PBMC-based new approach method reveals PFAS-driven T-cell proliferation and immune dysregulation

Abstract Immunotoxicity has emerged as a key health concern for per- and polyfluoroalkyl substances (PFAS), with animal studies showing reduced T-dependent antibody responses (TDAR) and epidemiological studies reporting decreased vaccine antibody titres. Notably, immunotoxicity i...