Lauren Lubeck

Regional signaling controls stem cell-mediated regeneration in an invertebrate chordate

Many tissues harbor quiescent stem cells that activate after injury, yet how local signals regulate this transition is not well understood. The solitary ascidian Ciona robusta provides a unique model, as bottom body fragments regenerate while upper fragments fail to do so. By com...

Distinct cell states define larval and adult body plans in a hemichordate

Abstract A major gap in our understanding of animal development is how adult body plans arise in animals with indirect development, where adults emerge from the transformation of a distinct larval form during metamorphosis. We address this question by examining cellular changes i...