Lan Luo

Extracellular vesicle-derived circ6853 drives vascular remodeling and serves as a potential biomarker and therapeutic target for gastric cancer

Gastric cancer (GC), a leading global malignancy, urgently requires the discovery of novel diagnostic and therapeutic targets. The roles of extracellular vesicle (EV)- derived circular RNAs (circRNAs) as diagnostic biomarkers and functional regulators, particularly in vascular re...

Bioactive PCL/nSi-BMSCs composite scaffold regulates periosteal cell functions for neurovascularized bone regeneration

Proper innervation and vascularization are not only essential for maintaining bone homeostasis but also play a pivotal role in orchestrating efficient bone regeneration. Here, we investigate the regenerative potential of a polycaprolactone/Nanosilicates (PCL/nSi) scaffold loaded...