Kyudong Han

Host–Microbe Crosstalk in Sjögren’s Disease: Epithelial Type I Interferon Amplification, Loss of Short-Chain Fatty Acid Restraint, and the Effector-Phase Focus of Validated Therapy

Sjögren’s disease (SjD) is a systemic autoimmune disease of the exocrine glands, long framed as a lymphocyte-driven disorder in which immune cells destroy the target tissue. Genomic, epigenetic, microbiome, and single-cell and spatial studies have since shown the glandular epithe...

Comparative evaluation of 16S rRNA sequencing strategies reveals superior resolution of the healthy Korean salivary microbiome by full-length sequencing

Although next-generation sequencing has elucidated complex microbial networks within the human oral cavity, current analyses remain predominantly limited to genus-level resolution, and most of the human oral microbiome landscape is based on Western population datasets. Because th...