Kyoshiro Hiki

Short‐Term 6PPD‐Q Exposure alters Tight‐Junction‐Related Gene Expression Without Acute Lethality in Japanese Medaka Oryzias latipes

6PPD-quinone (6PPD-Q), a transformation product of the tire antioxidant 6PPD, causes acute mortality in several salmonid species, but its toxicity varies markedly among fish species. Disruption of vascular-barrier integrity and inflammatory signaling has been proposed as a key me...