Kyle D. Allen

Neurodegeneration and inflammation in a novel spinocerebellar ataxia 13 preclinical model

Abstract Neuroinflammation is a critical pathological feature underlying neurodegenerative diseases. Spinocerebellar ataxia 13 (SCA13) is a heterogeneous ataxia with several allelic variations of differing phenotypes. All are neurodegenerative and currently without effective trea...