Kunying Chen

Glucomannan from Aloe vera Gel Strengthens Intestinal Barrier by Suppressing Macrophage M1 Polarization via the Lactic Acid–Piezo1–Ca2+ Axis

Abstract Modulating intestinal macrophage polarization is critical for maintaining intestinal barrier integrity. Our previous study demonstrated that glucomannan from Aloe vera gel (AGP) improved the intestinal barrier, yet its direct impact on intestinal macrophages remained und...