Author
Kunfan Zhang
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Recent research
- BiologyOpen access
A Novel Synthesis of 5-HT4 Receptor Intestinal-Restrictive Bivalent Agonist: SIPI11588
SIPI11588 is a 5-HT4 receptor agonist with potential bioactivity that significantly enhances whole-gut and colonic transit and defecation. The original linear synthetic route, starting from 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid (3), involving seven steps (37.91...