Kun Chen

Antibacterial Cyclic Oligo(disulfide)s with Tunable Hydrophilicity Dictate Membrane Interactions and Distinct Metabolic Interference

Abstract To combat drug-resistant bacteria, antimicrobial agents with tunable and multi-modal mechanisms are urgently needed. While membrane-disrupting polymers have been widely explored, precisely regulating their membrane interactions and downstream metabolic effects remains ch...

From Alarms to Probabilities: Stratified Human Review, Label-Noise Correction, and Calibrated Risk Grading for Industrial Vibration Anomaly Detection

Industrial anomaly detectors emit binary alarms, but production lines need graded dispositions. Calibrating alarms into fault probabilities requires ground truth, coming only from noisy human review treated as exact. We report a deployed closed loop on a reciprocating-compressor...