Kuan-Chou Chen

Carbonyl stress promotes ferroptotic susceptibility through lipid metabolic remodeling in renal tubular epithelial cells

Diabetic kidney disease (DKD) is a leading cause of chronic kidney disease worldwide and is characterized by progressive tubular injury, oxidative stress, and metabolic dysregulation. Carbonyl stress, driven by the accumulation of reactive dicarbonyl metabolites such as methylgly...