Kshitiz Paudel

Deficiency of ROR$${\rm{\gamma }}$$t promotes inflammation and compromises bacterial clearance in a mouse model of cystic fibrosis-like lung disease

Cystic fibrosis (CF) leads to dehydration of the airway surface liquid layer, resulting in hyperconcentrated mucus, airway obstruction, chronic lung inflammation, bronchiectasis, alveolar space enlargement, compromised mucociliary clearance, and increased susceptibility to bacter...