Krzysztof Guzik

Endothelial senescence impairs efferocytosis and alters macrophage responses: insights into APP-CD74 signaling

Abstract Background Endothelial cell senescence contributes to vascular aging and chronic inflammation, yet its impact on endothelial–macrophage interactions remains poorly understood. Here, we combined functional assays, global proteomics, 3D co-culture spheroid models, and sing...