Koushan Sineh Sepehr

Treatment-associated changes in SESN2, NFATC1, and NRF2 gene expression in rheumatoid arthritis: a comparative study of newly diagnosed and DMARD-treated patients

Rheumatoid arthritis (RA) is an autoimmune disorder characterized by uncontrolled joint inflammation and progressive structural damage in the joints. Sestrin 2 ( SESN2 ) and nuclear factor erythroid-related 2 ( NRF2 ) acts as critical regulators of cellular redox homeostasis and...