Kota KOMATSU

Localization and functional difference of MSA-2 paralogs in Babesia bovis merozoites

Babesia bovis merozoite surface antigen 2 (MSA-2) proteins are encoded by members of the msa multigene family and are implicated in erythrocyte recognition and invasion, yet their roles remain only partially understood. We investigated spatiotemporal differences among three MSA-2...

Identification of Small-Molecule Inhibitors of Babesia bovis by High-Throughput SYBR Green I Screening

Background: Bovine babesiosis, caused by Babesia bovis, remains a major constraint to cattle production in endemic regions, while the current control relies on only a few drugs with concerns over resistance and residues. Methods: This study screened 9600 chemically diverse compou...