Konstanze Guggenberger

NLRP3 Marks an Inflammatory Neutrophil–NETosis–Pyroptosis Network in Human Ischemic Stroke Thrombi

Background: Human ischemic stroke thrombi are increasingly recognized as biologically active immunothrombotic structures. While the NLRP3 inflammasome contributes to experimental stroke pathology, its role within human cerebral thrombi remains poorly understood. Methods: Thrombi...