Kimihiro Yamashita

Electrical Surface Polarization as a Functionalization Strategy to Improve Bone Regeneration of Apatite‐Based Graft Materials

ABSTRACT Apatite‐based bone graft materials are widely used for bone repair; however, their limited bioactivity and slow remodeling often hinder replacement by newly formed bone. Electrical surface polarization has emerged as a promising strategy for modifying the surface propert...

Can Chemoradiotherapy Expand Immune Checkpoint Blockade Responsiveness in Mismatch Repair‐Proficient Rectal Cancer?

ABSTRACT Immune checkpoint blockade (ICB) has transformed the treatment of mismatch repair‐deficient (dMMR) colorectal cancer but produces no meaningful benefit in advanced mismatch repair‐proficient (pMMR) disease. In the neoadjuvant setting, however, pathological responses have...