Kevin Zhang

Nutrients May Play a Complex Role in Influencing Microbiota Composition and Function in Parkinson’s Disease Patients

Parkinson's disease is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons, leading to symptoms such as tremors and gastrointestinal dysfunction. Previous studies have shown reduced gut microbial diversity and imbalances in Parkinson’s disea...

Multi-modal meta-analysis of functional genomics data to identify regulatory relationships in the brain

Assigning target genes to a transcription factor (TF) is a persistent challenge in gene regulatory biology. No single assay directly observes a regulatory relationship, and the commonly used individual data types, perturbation-response transcriptomics, chromatin immunoprecipitati...