Kenjirou Higashi

In Situ X-ray Scattering for Doxorubicin-Loaded Liposomes to Elucidate the Morphological Change Mechanism Depending on the Cooling Rate and Cholesterol Content

Abstract Doxorubicin (DOX)-loaded liposomes are one of the most established and clinically relevant nanomedicines in a drug delivery system. In this study, we elucidate the mechanistic relationships among cooling rate, lipid composition, and the resulting morphological evolution...