Kenji Wakai

Triangulating Evidence on Serum Uric Acid and Cancer Risk: Consistent Inverse Associations With Lung Cancer

ABSTRACT We examined the association between serum uric acid (UA) levels and cancer incidence through a conventional observational and two‐sample Mendelian randomization (MR) study in the same population (triangulation). We followed 13,695 individuals aged 35–69 years for cancer...

Serum soluble Fas levels and incidence of biliary tract cancer in a nested case-control study

Abstract Background: Soluble Fas (sFas) plays multiple roles in tumorigenesis and cancer dissemination by avoiding apoptosis via connection to Fas ligand. We assessed associations of serum sFas levels with the incidence of extrahepatic biliary tract cancer (eBTC) in a prospective...

Associations of Happiness, Ikigai, and Enjoyment of Daily Life with Frequency of Forest Walking in a Japanese General Population: The Japan Multi-Institutional Collaborative Cohort Daiko Study

A number of studies have examined the acute effects of shinrin-yoku (forest bathing), or forest walking; however, only a limited number of epidemiological studies have examined the association between habitual forest walking and daily health. The aim of this study was to examine...