Kenan Gören

Synthesis, DFT Characterization and In Silico Evaluation of 1-(4-Methylpiperazin-1-yl-methyl)-3-benzyl-4-(4-hydroxybenzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5-one (MBHT)

In this study, the compound 1-(4-methylpiperazin-1-yl-methyl)-3-benzyl-4-(4-hydroxybenzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5-one (MBHT), synthesized using the Mannich reaction, was comprehensively investigated using theoretical methods. The stable geometry of the molecule...

Spectroscopic Characterization, DFT Analysis, Molecular Docking and ADMET Evaluation 1-(4-Methylpiperazin-1-ylmethyl)-3-p-chlorobenzyl-4-(4-hydroxybenzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5-one

In this study, 1-(4-metilpiperazin-1-il-metil)-3-p-klorobenzil-4-(4-hidroksibenzilidenamino)-4,5-dihidro-1H-1,2,4-triazol-5-on (PCHT), a Mannich base derived from 1,2,4-triazole, was synthesized and its structural properties were investigated using both experimental and theoretic...