Kelong Fan

Optimizing Vanadium Single‐Atom Nanozyme via Cluster‐Mediated Charge Orchestration for Modulating Immune Homeostasis in Intracerebral Hemorrhage

ABSTRACT Intracerebral hemorrhage (ICH) triggers excessive reactive oxygen species (ROS) accumulation and persistent neuroinflammation, which synergistically drive progressive neuronal damage and poor neurological functional recovery, severely restricting patient prognosis. Artif...

Ferromagnetic Coupling in Dual‐Atom Nanozymes Enables Spin‐Favorable Catalase‐Like Catalysis for Rheumatoid Arthritis Therapy

ABSTRACT Iron dual‐atom (Fe DA) nanozymes, structurally analogous to natural catalase, exhibit promising catalase‐like (CAT‐like) activity, yet further improving their catalytic performance and elucidating the underlying mechanism remain major challenges. Herein, we developed a c...

Spatiotemporal-switchable 2D NIR-II single-atom nanozyme for single-cell–level surgical navigation and glioblastoma phototherapy

Single-cell–level resolution tumor therapy represents an advanced strategy against glioblastoma but lacks suitable theranostic agents. Here, we developed a spatiotemporal-switchable, two-dimensional (2D), bismuthene-based second near-infrared window (NIR-II) nanozyme. In this pla...