Katsuhiro Kita

Colorectal Cancer and the Enigma Surrounding Non-Canonical Wnt Signaling

Since the discovery of truncated mutations of adenomatous polyposis coli proteins in familial adenoma patients in 1991, the mechanism of cytosolic β-catenin regulation has been intensively studied, and now it is very well known that the central role of the canonical Wnt/β-catenin...