Kathrin Schilling

Climate-amplified wildland–urban interface disasters create persistent internal metal mixtures associated with pulmonary impairment

Wildland–urban interface (WUI) wildfires are increasingly important climate-related exposure events because they burn built infrastructure and can mobilize legacy contaminants in addition to generating smoke. Although the acute respiratory effects of wildfire smoke are well descr...

An iron-regulated methionine redox axis governs adipose browning and cancer cachexia

Abstract Adipose browning and atrophy are early events of cachexia, a lethal metabolic disorder affecting nearly half of the population with cancer. Here, using individual-derived specimens and mouse models, we identified an iron-dependent pathway that initiates adipose browning...