Kathrin Möllenhoff

Identification of Changes in Gene Expression

ABSTRACT Evaluating the change in gene expression is a common goal in many research areas, such as in toxicological studies, which are particularly important in pre‐clinical research. In practice, the analysis is often based on multiple t ‐tests evaluated at the observed time poi...

Capturing Heterogeneous Time‐Variation in Covariate Effects in Non‐Proportional Hazard Regression Models

ABSTRACT A central focus in survival analysis is examining how covariates affect survival time. These covariate effects are often found to be either time‐varying, heterogeneous—such as being specific to patients, treatments, or subgroups—or exhibit both characteristics simultaneo...