Katarzyna Trzos

Fenofibrate, but not fenofibric acid, reduces fenestrations and impairs endocytic function in liver sinusoidal endothelial cells

Abstract Fenofibrate is widely prescribed for hyperlipidaemia and has been associated with rare but severe cases of drug-induced liver injury (DILI), yet its effects on liver sinusoidal endothelial cells (LSECs) remain to be investigated. LSECs maintain a highly permeable special...