Karthik Prakash

Primary tumor resection versus systemic therapy alone in patients with colorectal cancer and unresectable distant metastases: a systematic review and meta-analysis

Abstract Background The role of primary tumor resection (PTR) in patients with colorectal cancer (CRC) and unresectable distant metastases remains controversial. While PTR may prevent tumor-related complications, it delays systemic therapy and carries surgical risks. This systema...