Karsten Tedin

Population size modulates the transition from gene amplification-mediated heteroresistance to stable resistance

Abstract Heteroresistance is characterized by antibiotic-resistant subpopulations which can be underpinned by reversible gene duplication-amplification (GDA) of antibiotic resistance genes. It is often considered a precursor of stable resistance mutations. We investigated the evo...

Motion Anisotropy of Individual, Unconfined Rod-Like-Shaped Salmonella Typhimurium Bacteria

Abstract With the continuous advancement of microscopic imaging techniques, the motion of micro- and nanosized particles can be followed with increasing spatial and temporal accuracy. Analyzing the tracks of single particles enables one to address a broad range of scientific ques...