Karla Valeria Ibarra Mena

Integrative Experimental and Molecular Docking Analyses Reveal Phenanthroline Derivatives as Inhibitors of Cyanide-Resistant Respiration in Candida albicans

Background: Candida albicans can adapt to inhibition of the classical mitochondrial respiratory chain by activating an alternative oxidase (AOX)-dependent pathway, whereas Candida glabrata lacks detectable AOX-mediated respiration under the conditions tested. Identifying compound...