Karimov Zafar

Mitochondrial dysfunction and renal tubular injury in malignancy-associated hypercalcemia; a mechanistic framework for acute kidney injury in advanced renal cancer

Malignancy-associated hypercalcemia represents a severe metabolic complication frequently observed in advanced renal cell carcinoma (RCC), often precipitating acute kidney injury (AKT) and limiting therapeutic options. Though systemic volume depletion and renal vasoconstriction c...