Karim Osouli Bostanabad

Mechanism-Guided Combination Pharmacology of Curcumin and Methotrexate: Translational Strategies in Cancer and Emerging Applications in Rheumatoid Arthritis

Abstract Methotrexate (MTX) remains a cornerstone therapy in oncology and, to a lesser extent, rheumatoid arthritis (RA), yet its clinical utility in both settings is constrained by dose-limiting toxicities, interpatient pharmacokinetic variability, and the development of therape...