Kalyani Sanagavarapu

The Abundance of Phenylalanine in the DNAJB6b Linker Governs Its Role in Amyloid Suppression

Abstract The molecular chaperone DNAJB6b inhibits the disease-related self-assembly of amyloid peptides in an efficient and ATP-independent manner. The molecular basis for this action is not yet fully understood, but the low-complexity region of DNAJB6b as a stand-alone peptide d...