Kaizhen Peng

SIL1 modulates Reelin signaling during cortical neuron migration

Abstract SIL1 , a nucleotide exchange factor for the endoplasmic reticulum chaperone BiP, primarily binds nascent polypeptides to facilitate proper protein folding. It is a causative gene of Marinesco-Sjögren syndrome (MSS). Previous studies have indicated that SIL1 dysfunction d...