Kaikai Chen

GSDMB synergizes anti-PD-1 efficacy via Sema7a-mediated CD8+ T Cell infiltration in bladder cancer

Gasdermin B (GSDMB) is highly expressed in bladder cancer (BLCA) and has been implicated in anti-tumor immunity, yet its functional role and underlying mechanisms in enhancing the efficacy of immune checkpoint inhibitors (ICIs) remain unclear. Herein, we demonstrate that GSDMB sy...