Kai Xiong

Iterative Optimization of Photoactivatable BRD4 Degraders for Aging‐Amplified Immunotherapy in Patient‐Derived Lung Cancer Organoids

ABSTRACT Cancer remains a major global health threat. Targeted protein degradation (TPD) has revolutionized the modulation of protein function in therapeutic development. Nevertheless, the design of current TPD agents continues to face challenges, including hook effects and, more...