Jutturong Ckumdee

Development of loop-mediated isothermal amplification (LAMP) combined with a lateral flow dipstick DNA biosensor for detection of α thalassemia 1 [Southeast Asia (SEA), --SEA deletion]

This study aimed to develop a one-step loop-mediated isothermal amplification combined with a lateral flow dipstick (LAMP-LFD) DNA biosensor for the detection of α 0 -thalassemia (SEA deletion). Genomic DNA was obtained from 48 α 0 -thalassemia (SEA deletion)-positive and 48 (SEA...

Rapid simultaneous detection of katG S315T and rpoB S531L mutations for molecular screening of multidrug-resistant tuberculosis using a dual LAMP-lateral flow assay

ABSTRACT The global spread of multidrug-resistant tuberculosis (MDR-TB) remains a major challenge to tuberculosis control programs, particularly in resource-limited settings where access to rapid molecular drug-susceptibility testing is limited. Resistance to isoniazid and rifamp...