Junxian Du

AP2M1 promotes TNBC progression by stabilizing EGFR through inhibition of lysosomal degradation

Triple-negative breast cancer (TNBC) is an aggressive and heterogeneous malignancy, with 50–80% of cases exhibiting elevated EGFR expression. Dysregulated endocytic trafficking contributes to sustained receptor signaling and tumor progression, suggesting endocytosis as a potentia...