Junko Isobe

Genomic diversification and modular recombination of Stx2 prophages associated with chromosomal integration sites during an STEC O111 and O157 outbreak

ABSTRACT Shiga toxin 2 (Stx2) production in Shiga toxin-producing Escherichia coli (STEC) is mediated by lambdoid Stx2-converting bacteriophages, which play a central role in the evolutionary and pathogenic potential of STEC lineages. However, the mechanisms through which Stx2 ph...