Junjun Chen

Association between lipid accumulation product index (LAP index) and coronary artery disease risk

Coronary artery disease (CAD) is a highly prevalent condition that predominantly affects obese individuals and those with metabolic abnormalities. The lipid accumulation product (LAP), combining waist circumference (WC) and triglyceride (TG) measurements, provides a clinically re...

Integrated analysis of bulk transcriptomics and single-cell transcriptomics revealed the association characteristics between heart failure and β-hydroxybutyrylation-related genes

Background As a major cause of global mortality, heart failure (HF) has mechanisms that remain elusive. Recent studies suggest β-hydroxybutyrylation (Kbhb) may contribute to its pathogenesis, driving this investigation into Kbhb-associated HF biomarkers. Methods We collected HF-a...