Junjie Xie

A programmed sequential organelle-targeted nanoattack strategy for cGAS-STING hyperactivation and potentiated systemic cancer immunotherapy

Cancer immunotherapy is hindered by insufficient immunogenic cell death (ICD) and suboptimal cGAS-STING activation. While organelle-targeted therapies hold promise, conventional treatments often fail because single-target attacks are neutralized by tumor buffering networks, where...