Jung Hee Park

Lipid Mediators Derived from Docosahexaenoic Acid Alleviate Periodontal Inflammation and Alveolar Bone Loss in Periodontitis Associated with Suppression of the NF-κB and STAT3 Signaling Pathways

Background: Lipid mediators (LM), comprising 17S-hydroxy-docosahexaenoic acid, resolvin D5, and protectin DX in a ratio of 3:47:50, were naturally generated from docosahexaenoic acid by soybean lipoxygenase and exhibit potent anti-inflammatory activities. However, their therapeut...