Jun Zou

TLR3 Overexpression Attenuates D-GalN/LPS-Induced Acute Liver Injury and Is Associated With AMPK Phosphorylation, Autophagy-Related Changes, and IRF3 Upregulation

Background: Toll-like receptor 3 (TLR3) has been implicated in innate immune regulation, but its role in acute liver injury is unknown. The aim of this study was to investigate the functional significance of TLR3 and its underlying mechanisms in D-GalN/lipopolysaccharide (LPS)-in...