Author
Jun Wang
Recent research
- Materials & Energy
Abstract An efficient kinetic resolution of binaphthyl triflates is developed via Ni-catalyzed asymmetric C(sp2)–P cross-coupling to access substituted atropisomeric phosphines. Moreover, the phosphine framework showed superior reactivity and enantiocontrol in Pd-catalyzed asymme...
- Biology
“Trojan”Methionine Probe Reveals PKM2as a Methionine-Sensing Protein in the mTORC1 Pathway
Abstract Methionine (Met) plays a pivotal role in numerous cellular functions. Methionine restriction has been demonstrated to provide metabolic benefits in aging, obesity, diabetes and as an adjunct to cancer therapy. However, the methionine-sensing proteins and how cells direct...