Jun Shu

Decomposition of the systemic immune-inflammation index reveals neutrophil- and lymphocyte-driven, non-linear risk of progression from mild cognitive impairment to dementia

The progression from mild cognitive impairment (MCI) to dementia represents a critical intervention window. The systemic immune-inflammation index (SII) integrates neutrophil, platelet, and lymphocyte counts and has been proposed as an accessible marker of this progression. Becau...