Jun-Ichi Sakamaki

p62/ SQSTM1 : From an autophagy receptor to a condensate organizer of selective autophagy and stress signaling

Upon exposure to stress, cells activate a variety of stress-response and quality-control mechanisms to maintain homeostasis. Dysregulation of these processes is implicated in numerous diseases, including cancer, liver disorders, and neurodegenerative diseases. p62/Sequestosome 1...