Julie A. Moreno

Alzheimer’s disease neuropathological characterization of the dog brain and relationship to biofluid biomarkers and cognitive function

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder affecting more than 55 million people worldwide and is characterized by cognitive decline, amyloid-beta (Aβ) plaques, and neurofibrillary tangles. Although transgenic rodent models have advanced understanding of...

Wildfire Smoke Exposure Accelerates Age-Related Functional Decline in Caenorhabditis elegans

Wildfire smoke (WFS) is an expanding source of fine particulate matter (PM2.5) with well-documented cardiopulmonary risks, yet its impact on organismal aging and functional decline remains incompletely understood. Here we use the nematode Caenorhabditis elegans to characterize th...